Zora Biosciences is a service provider for the pharmaceuticals industry and a diagnostics discovery company, with a particular focus on metabolomic analyses. It is the only specialist in this field in the Nordic region, and one of only around 10 worldwide.
Zora studies all the small molecules, or metabolites, in a given organism using highly sophisticated laboratory methods, such as mass spectrometry, coupled to a battery of bioinformatic tools – to provide a highly detailed overview of the multitude of factors influencing a biological system at a particular point in time.
The resulting metabolomic profiles highlight a variety of disease-related issues and the effect of possible drug intervention, as well as the impact that people’s dietary habits, exercise regimes, and any infectious organisms in their bodies may have.
Compared to genomic testing, which concentrates on one or several genes to predict the risk for certain afflictions and is unable to factor in environmental influences, metabolomic analyses provide what is virtually an online read-out of a complete biological system.
Metabolomic analyses can benefit a number of areas, most notably pharmaceutical development. Metabolomic screening can help a drug company save on costs and shorten the time to market for new drugs, for example, through the use of novel biomarkers.
This approach can simplify the elimination of toxic drug candidates, generate new efficacy and safety markers for drug development work, identify drug responder groups and subpopulations sensitive to a drug, and provide new insights on the mechanisms that make a drug work.
Zora offers its customers a best-in-class selection of metabolomic tools and systems, particularly in the area of lipidomics, a unique Zora competence. This represents an importance resource, as lipid molecules play a key role in many therapeutic areas, such as cardiovascular disease, diseases of the central nervous system, diabetes, and obesity.
|Metabolomics holds great promise not only in drug development, but also for disease diagnostics and more targeted and personalised medication – and Zora Biosciences is one of the few companies anywhere specialising in the field.